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Empty large liposomes reduce cartilage degeneration in osteoarthritic rats by forming a lubricative coating
Osteoarthritis and Cartilage
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February 2025
Duration of clinically meaningful analgesic response to intra-articular MM-II, a novel suspension of large, empty, multilamellar liposomes, in patients with painful knee osteoarthritis: Analysis from a 26-week phase 2b andomised controlled trial
Link to Presentation
European Alliance of Association for Rheumatology (EULAR)
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June 2024
Volume of intra-articular placebo injection has no effect on pain in knee osteoarthritic patients: Post hoc analyses from a phase 2b, double-blind, randomized trial
Link to Poster
Osteoarthritis and Cartilage
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April 2024
Efficacy and Safety of a Single Intra-Articular Injection of MM-II, a Novel Suspension of Large, Empty, Multilamellar Liposomes, in People with Painful Knee OA: Results of a 26- Week, Phase 2b, Placebo-Controlled, Double-Blind, Randomized Trial
American College of Rheumatology (ACR)
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November 2023
Intra-articular MM-II, a novel suspension of large empty multilamellar liposomes, in painful knee osteoarthritis: A 26-week phase 2b placebo-controlled double-blind randomized trial
Link to Poster
Osteoarthritis Research Society International (OARSI)
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March 2023
Cartilage-bound large multilamellar liposomes show potential cartilage protection from inflammatory stimulus by attenuating aggrecan degredation
Link to Poster
Osteoarthritis Research Society International (OARSI)
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March 2023
Large multilamellar neutral liposomes form a stable layer on articular cartilage surface under ex-vivo physiological compression
Link to Poster
Osteoarthritis and Cartilage (OARSI)
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April 2022
Local and systemic effects following intraarticular injection of MM-II liposomes. Results from two nonclinical toxicity studies in rabbits and dogs
Osteoarthritis and Cartilage (OARSI)
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April 2021
Intraarticular injection of mm-ii liposomes lubricates cartilage in-vivo and reduces friction and wear in ex-vivo cartilage models
Link to Poster
Osteoarthritis and Cartilage (OARSI)
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April 2020
Safety and Efficacy of Liposome Intra-Articular Injection in Moderate Knee Osteoarthritis. a Prospective Randomized Double-Blinded Study
2014 ACR/ARHP Annual Meeting
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November 2014
Safety and efficacy of MM-II, an intra-articular injection of liposomes, in moderate knee osteoarthritis. Prospective randomized double-blinded study
Osteoarthritis research Society International (OARSI)
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April 2014
Liposomes as potential biolubricant additives for wear reduction in human synovial joints
Science Direct
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March 2010
Liposomes act as effective biolubricants for friction reduction in human synovial joints
ACS Publications
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January 2010